Cannabis, also known as marijuana, is a plant grown in many parts of the world, and has been used for medicinal purposes dating back to ancient times. It produces a resin containing compounds called cannabinoids.
These Cannabinoids are active chemicals in Cannabis that cause drug like effects throughout the body, including the central nervous system and the immune system. Some of these cannabinoids are psychoactive and act on the brain by changing mood or consciousness. Cannabinoids can be taken by mouth, inhaled, or sprayed under the tongue.
In the United States, federal and state laws regarding the medical use of cannabis and cannabinoids are in conflict and have led to confusion among patients, caregivers, and healthcare providers. Currently, cannabis is legal for medical purposes in 50% of the states, and another seventeen states allow products that are high in cannabidiol (CBD) and low in THC (tetrahydrocannabinol) for medical use.
On the FDA’S website Questions and Answer about Marijuana, they said that cannabis has not be approved, because according to them, there’s not enough research that prove that can be safe or effective for the treatment of any disease or condition. Also, The FDA only supports researchers who conduct adequate and well-controlled clinical trials which may lead to the development of safe and effective marijuana products to treat medical conditions.
However, there is actually a lot of scientific research on cannabis and its effectiveness in curing not only cancer but many other conditions. So, the question remains the same: Why does the FDA not approve the use of medical cannabis? Perhaps the answer to that question is because it is something organic and natural that can not give it to them and Big Pharma, the income that they want.
There is no doubt that cannabinoids are interesting biological molecules. Hundreds of scientists around the world are investigating their potential in cancer and other diseases, brought together under the blanket organization The International Cannabinoid Research Society.
Researchers first looked at the anticancer properties of cannabinoids back in the 1970s, and many hundreds of scientific papers looking at cannabinoids and cancer have been published since then. Let’s take a closer look at the evidence!
Cannabinoids decrease tumor progression by at least 2 mechanisms: apoptotic death (tumor cells) and the inhibition of tumor angiogenesis. A study published in the British Journal of Cancer, conducted by the Department of Biochemistry and Molecular Biology at Complutense University in Madrid, determined that THC and other cannabinoids inhibit tumor growth. THC was found to decrease tumour cells in two out of the nine patients, and the delivery was safe and was achieved with zero psychoactive effects.
Additionally, Lu found that when THC and CBD were used together to treat tumors, researchers could use less of each compound and still achieve the same effects. This is important because THC is psychoactive and can cause unwanted psychoactive side effects for people receiving treatment. Fortunately, when combined with CBD, THC can be used in smaller doses and patients receiving treatment can reap the medical benefits of the compound without any of the "high" feelings traditionally associated with it.
A study published in The Journal of Neuroscience, examined the biochemical events in both acute neuronal damage and in slowly progressive, neurodegenerative diseases. They conducted a magnetic resonance imaging study that looked at THC (the main active compound in marijuana) and found that it reduced neuronal injury in rats. The results of this study provide evidence that the cannabinoid system can serve to protect the brain against neurodegeneration.
As remarkable as it may seem, there is reliable and growing for-real evidence suggesting that cannabis can slow the growth of tumors by hindering their ability to hijack blood vessels for their own nefarious purposes (angiogenesis), hamper the migration of cancer cells throughout the body (metastasis), and actually hasten the death (autophagy and apoptosis) of these otherwise uncontrollably proliferating rogue cells. In other words, cannabis really does fight cancer.
A study published in the US National Library of Medicine, conducted by the California Pacific Medical Centre, determined that cannabidiol (CBD) inhibits human breast cancer cell proliferation and invasion. They also demonstrated that CBD significantly reduces tumour mass. Another study published in the journal Molecular Cancer showed that THC reduced tumour growth and tumour numbers. They determined that cannabinoids inhibit cancer cell proliferation, induce cancer cell apoptosis, and impair tumour angiogenesis (all good things). This study provides strong evidence for the use of cannabinoid-based therapies to manage breast cancer.
While smoking marijuana is never good for the lungs, the active ingredient in marijuana may help fight lung cancer. A study published in the journal Oncogene by Harvard Medical School’s Experimental Medicine Department determined that THC inhibits epithelial growth factor induced lung cancer cell migration and more. They go on to state that THC and other cannabinoids should be explored as novel therapeutic molecules in controlling the growth and metastasis of certain lung cancers.
Also, a study published in the US National Library of Medicine by the Institute of Toxicology and Pharmacology in Germany determined that cannabinoids inhibit cancer cell invasion. Effects were confirmed in primary tumour cells from a lung cancer patient. Overall, data indicated that cannabinoids decrease cancer cell invasiveness.
The use of medical marijuana for prostate cancer is causing more men to look into this controversial treatment. One of the most common medical uses of marijuana is for cancer symptoms and the side effects of treatment such as chemotherapy, but studies on people who have used the drug are proving that marijuana may also have some anti-tumor effects.
A study in Italy analyzed the effect of cannabidiol (CBD) on prostate cancer. These chemicals are not related to THC, the component that makes one “high” with marijuana. The researchers found that CBD was effective in killing prostate carcinoma. It also prevented its growth and spread. They also found that the chemicals in cannabis enhance each other’s cancer-killing properties.
Also, in 2009, a team of researchers from the University of Alcalá in Spain published a study in the British Journal of Cancer that adds merit to the thought. It suggests that cannabinoid treatments could inhibit prostate cancer cell growth through activation of the CB2 receptors. All in all, the study involved three human prostate cancer cell lines – PC-3, DU-145, and LNCaP. Results show that a chemical similar to anandamide (the body’s natural version of THC) inhibited PC-3 cell growth. They experienced the same results with JWH-015, a synthetic CB2 receptor agonist.
Blood cancers affect the production and function of your blood cells. Most of these cancers start in your bone marrow where blood is produced. Stem cells in your bone marrow mature and develop into three types of blood cells: red blood cells, white blood cells, or platelets. In most blood cancers, the normal blood cell development process is interrupted by uncontrolled growth of an abnormal type of blood cell. These abnormal blood cells, or cancerous cells, prevent your blood from performing many of its functions, like fighting off infections or preventing serious bleeding.
Common treatments are chemotherapy, radiotherapy and, in some cases, a stem cell or bone marrow transplant. However, cannabis is also a natural alternative that can kill cancer cells.
In 2016, an experiment published in BioMed Central Cancer found that the psychoactive component in cannabis, THC, successfully halted the proliferation of leukemia cell cultures. The study used the drug dronabinol, which is a synthetic drug designed to resemble and mimic the effects of THC. The researchers found that the drug was most effective in acute lymphoblastic and myeloid leukemia cells.
Also cancer research has shown that cannabis compounds can trigger apoptosis in tumor cells, which is a hallmark of an effective cancer drug. In 2006, a study published in Molecular Cancer Research found that THC treatment successfully triggered apoptosis in cultured leukemia T cells.
Additional research has shown that cannabis compounds are anti-metastatic, which prevents tumor cells from infecting other areas after a tumor develops. In the laboratory, cannabis compounds also prevent tumor cells from establishing blood vessels. Without blood vessels, the tumors starve.
Due to an increase in national marijuana usage, state-by-state legalization, and an overall laissez-faire societal view, questions have arisen relating marijuana use to oral cancer development. Does the smoke from marijuana or the properties associated with its chemical nature lead to oral cancer?
The overall consensus among researchers is no. According to Norml.org, cannabis smoke — unlike tobacco smoke — has not been definitively linked to cancer in humans. Cannabis smoke contains many of the same carcinogens as tobacco smoke … but just not the cancer-causing carcinogens. In fact, cannabis also contains cannabinoids, such as THC, which contain anticancer properties. A study published by the US National Library of Medicine shows that cannabinoids are potent inhibitors of cellular respiration and are toxic to highly malignant oral tumours.
The liver is the body’s primary detoxification organ. The filtering factory for all of our blood, it is particularly susceptible to certain kinds of cancers. Fortunately, recent research has found that cannabinoid therapy may halt the progression of the disease.
In 2015, Chinese researchers tested a synthetic cannabinoid called WIN55, 212-2 against HCC tumor cells. Cannabinoid is a man-made model of THC, the primary psychoactive in marijuana. The tumor cells were cultivated and treated outside the body.
Researchers observed that when cannabinoid is applied to the cells, the tumor growth seemed to stop. Cannabinoid stopped the development of the cancer cells by activating special receptors in the tumor. It engaged the cannabinoid receptor 2, which is a site that acts sort of like a lock, waiting for specific instructions from a chemical trigger.
Pancreatic cancer is a particularly aggressive form of cancer and is very difficult to treat. Unfortunately, the devastating condition is also on the rise. However, a study published in 2006 by a team of Spanish researchers, who found that cannabinoids – including natural and synthetic versions of THC – were able to reduce the growth of tumors in two different animal models of pancreatic cancer. Interestingly, the study found that while cannabinoids were able to induce apoptosis (cell death) of tumor cells, normal pancreatic cells were left unaffected.
As the name implies, ovarian cancer is cancer of the ovaries, and as such, only affects women. As the seventh-most common form of cancer for women, this is treated very seriously, particularly because it attacks such a vital part of the body, making surgery more complicated and dangerous.
Like most types of cancer, there is a wide variety of potential treatment options for ovarian cancer, including immunotherapy, chemotherapy, etc. However, there can be debilitating side effects to some treatments, as well as inherent risk, so, many people have turned to more natural forms of treatment for ovarian cancer: Cannabis.
A study with medical marijuana support a new therapeutic approach for the treatment of ovarian cancer. It is also conceivable that with available cannabinoids as lead compounds, non-habit forming agents that have higher biological effects could be developed.
As you can see cannabis is excellent for combating various types of cancer and even for fighting other diseases! Every day there is more and more research, which proves the effectiveness of this natural plant, although the FDA still does not see it as safe.
There is no doubt that the natural is winning its battlefield in medicine, it is time for us to start using it. Heal yourself naturally!
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